Summary for 4R8Q
Entry DOI | 10.2210/pdb4r8q/pdb |
Related | 4QPM |
Descriptor | Mitotic checkpoint serine/threonine-protein kinase BUB1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | spindle assembly checkpoint, mitosis, kinase, activation, ken box, cdc20, atp-binding, cell cycle, cell division, disease mutation, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O43683 |
Total number of polymer chains | 1 |
Total formula weight | 42323.39 |
Authors | Tomchick, D.R.,Yu, H. (deposition date: 2014-09-02, release date: 2014-11-12, Last modification date: 2024-02-28) |
Primary citation | Kang, J.,Yang, M.,Li, B.,Qi, W.,Zhang, C.,Shokat, K.M.,Tomchick, D.R.,Machius, M.,Yu, H. Structure and substrate recruitment of the human spindle checkpoint kinase Bub1. Mol.Cell, 32:394-405, 2008 Cited by PubMed: 18995837DOI: 10.1016/j.molcel.2008.09.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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