4R57

Crystal structure of spermidine N-acetyltransferase from Vibrio cholerae in complex with acetyl-CoA

Summary for 4R57

Entry DOI	10.2210/pdb4r57/pdb
Related	3EG7 4JJX 4JLY 4K4L 4MI4
Descriptor	Spermidine n1-acetyltransferase, ACETYL COENZYME *A, TETRAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, acetyl coenzyme a, spermidine, transferase
Biological source	Vibrio cholerae O1 biovar El Tor
Cellular location	Cytoplasm : Q9KL03
Total number of polymer chains	12
Total formula weight	261935.19
Authors	Filippova, E.V.,Minasov, G.,Kiryukhina, O.,Shuvalova, L.,Kuhn, M.L.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-08-20, release date: 2015-03-25, Last modification date: 2023-09-20)
Primary citation	Filippova, E.V.,Kuhn, M.L.,Osipiuk, J.,Kiryukhina, O.,Joachimiak, A.,Ballicora, M.A.,Anderson, W.F. A Novel Polyamine Allosteric Site of SpeG from Vibrio cholerae Is Revealed by Its Dodecameric Structure. J.Mol.Biol., 427:1316-1334, 2015 Cited by PubMed: 25623305 DOI: 10.1016/j.jmb.2015.01.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.079 Å)

Structure validation