4R3V
Structure of karilysin propeptide and catalytic MMP domain
Summary for 4R3V
Entry DOI | 10.2210/pdb4r3v/pdb |
Related | 2XS3 2XS4 4IN9 |
Descriptor | Karilysin, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | metzincin metallopeptidase, matrix metalloproteinase with unique propeptide, bacterial matrix metalloproteinase-like enzyme, hydrolase |
Biological source | Tannerella forsythia |
Cellular location | Secreted : D0EM77 |
Total number of polymer chains | 2 |
Total formula weight | 41394.91 |
Authors | Lopez-Pelegrin, M.,Ksiazek, M.,Karim, A.Y.,Guevara, T.,Arolas, J.L.,Potempa, J.,Gomis-Ruth, F.X. (deposition date: 2014-08-18, release date: 2015-01-07, Last modification date: 2023-09-20) |
Primary citation | Lopez-Pelegrin, M.,Ksiazek, M.,Karim, A.Y.,Guevara, T.,Arolas, J.L.,Potempa, J.,Gomis-Ruth, F.X. A novel mechanism of latency in matrix metalloproteinases. J.Biol.Chem., 290:4728-4740, 2015 Cited by PubMed: 25555916DOI: 10.1074/jbc.M114.605956 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
Download full validation report