4R0X
Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction
Summary for 4R0X
Entry DOI | 10.2210/pdb4r0x/pdb |
Descriptor | Peptidyl-prolyl cis-trans isomerase FKBP5 (2 entities in total) |
Functional Keywords | fk-506 binding domain, hsp90 cochaperone, immunophiline, peptidyl-prolyl isomerase, isomerase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q13451 |
Total number of polymer chains | 1 |
Total formula weight | 13487.48 |
Authors | LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.M.,Hernandez, G. (deposition date: 2014-08-02, release date: 2015-05-13, Last modification date: 2023-09-20) |
Primary citation | LeMaster, D.M.,Mustafi, S.M.,Brecher, M.,Zhang, J.,Heroux, A.,Li, H.,Hernandez, G. Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins. J.Biol.Chem., 290:15746-15757, 2015 Cited by PubMed: 25953903DOI: 10.1074/jbc.M115.650655 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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