4R0X
Allosteric coupling of conformational transitions in the FK1 domain of FKBP51 near the site of steroid receptor interaction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase FKBP5 | polymer | 122 | 13487.5 | 1 | UniProt (Q13451) Pfam (PF00254) | Homo sapiens (human) | PPIase FKBP5, 51 kDa FK506-binding protein, 51 kDa FKBP, FKBP-51, 54 kDa progesterone receptor-associated immunophilin, Androgen-regulated protein 6, FF1 antigen, FK506-binding protein 5, FKBP-5, FKBP54, p54, HSP90-binding immunophilin, Rotamase |
| 2 | B (A) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A: 20 - 140 (UniProt: Q13451)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | initiating methionine |
| Gly 121 | Lys 121 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13487.5 | |
| All* | Total formula weight | 13487.5 |
