4QXU
Novel Inhibition Mechanism of Membrane Metalloprotease by an Exosite-Swiveling Conformational antibody
Summary for 4QXU
Entry DOI | 10.2210/pdb4qxu/pdb |
Related | 4OUU 4P3C 4P3D |
Descriptor | anti_MT1-MMP Light chain, anti_MT1-MMP Heavy chain, Matrix metalloproteinase-14, ... (5 entities in total) |
Functional Keywords | structural genomics, psi-2, protein structure initiative, israel structural proteomics center, ispc, igg fold, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Membrane ; Single-pass type I membrane protein : P50281 |
Total number of polymer chains | 3 |
Total formula weight | 50642.37 |
Authors | Udi, Y.,Grossman, M.,Solomonov, I.,Dym, O.,Rozenberg, H.,Moreno, v.,Cuiniasse, P.,Dive, V.,Arroyo, A.G.,Sagi, I.,Israel Structural Proteomics Center (ISPC) (deposition date: 2014-07-22, release date: 2014-12-17, Last modification date: 2023-09-20) |
Primary citation | Udi, Y.,Grossman, M.,Solomonov, I.,Dym, O.,Rozenberg, H.,Moreno, V.,Cuniasse, P.,Dive, V.,Arroyo, A.G.,Sagi, I. Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23:104-115, 2015 Cited by PubMed: 25482542DOI: 10.1016/j.str.2014.10.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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