4QSY
SHP2 SH2 domain in complex with GAB1 peptide
Summary for 4QSY
Entry DOI | 10.2210/pdb4qsy/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 11, GRB2-associated-binding protein 1 (3 entities in total) |
Functional Keywords | sh2 domain, signalling, ptr binding, hydrolase-protein binding complex, hydrolase/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q06124 |
Total number of polymer chains | 2 |
Total formula weight | 13754.20 |
Authors | Gogl, G.,Remenyi, A. (deposition date: 2014-07-06, release date: 2015-07-08, Last modification date: 2023-12-06) |
Primary citation | Gogl, G.,Remenyi, A. Selective targeting of GAB adapter protein SHP2 tyrosine phosphatase interaction attenuates ERK signaling To be Published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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