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4QSY

SHP2 SH2 domain in complex with GAB1 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein phosphatase non-receptor type 11polymer10812150.61UniProt (Q06124)
Pfam (PF00017)
Homo sapiens (human)Protein-tyrosine phosphatase 1D, PTP-1D, Protein-tyrosine phosphatase 2C, PTP-2C, SH-PTP2, SHP-2, Shp2, SH-PTP3
2B
(B)
GRB2-associated-binding protein 1polymer131603.61UniProt (Q13480)Homo sapiensGRB2-associated binder 1, Growth factor receptor bound protein 2-associated protein 1
3C, D
(A, B)
waterwater18.053Chemie (HOH)
Sequence modifications
A: 1 - 106 (UniProt: Q06124)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight13754.2
All*Total formula weight13754.2
*Water molecules are not included.

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PDB entries from 2025-12-24

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