4QSR
Structure of the bromodomain of human ATPase family AAA domain-containing protein 2 (ATAD2) with bound MPD
Summary for 4QSR
Entry DOI | 10.2210/pdb4qsr/pdb |
Related | 4QSP 4QSQ 4QSS 4QST 4QSU 4QSV 4QSW 4QSX |
Descriptor | ATPase family AAA domain-containing protein 2, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
Functional Keywords | structural genomics consortium (sgc), signaling protein, bromodomain, actyl-lysine binding, atpase family aaa domain-containing protein 2, epigenetics |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : Q6PL18 |
Total number of polymer chains | 1 |
Total formula weight | 16092.26 |
Authors | Chaikuad, A.,Felletar, I.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2014-07-06, release date: 2014-07-23, Last modification date: 2023-09-20) |
Primary citation | Chaikuad, A.,Petros, A.M.,Fedorov, O.,Xu, J.,Knapp, S. Structure-based approaches towards identification of fragments for the low-druggability ATAD2 bromodomain MedChemComm, 5:1843-1848, 2014 Cited by DOI: 10.1039/C4MD00237GPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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