4QPD

Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with tetrahydrofolate

Summary for 4QPD

Entry DOI	10.2210/pdb4qpd/pdb
Related	4QPC 4TS4 4TT8 4TTS 4r8v
Descriptor	10-formyltetrahydrofolate dehydrogenase, DI(HYDROXYETHYL)ETHER, (6S)-5,6,7,8-TETRAHYDROFOLATE, ... (4 entities in total)
Functional Keywords	10-formyltetrahydrofolate dehydrogenase, hydrolase domain, catalysis, oxidoreductase
Biological source	Danio rerio (leopard danio,zebra danio,zebra fish)
Total number of polymer chains	2
Total formula weight	72461.40
Authors	Lin, C.C.,Chen, C.J.,Fu, T.F.,Chuankhayan, P.,Kao, T.T.,Chang, W.N. (deposition date: 2014-06-23, release date: 2015-04-15, Last modification date: 2024-03-20)
Primary citation	Lin, C.C.,Chuankhayan, P.,Chang, W.N.,Kao, T.T.,Guan, H.H.,Fun, H.K.,Nakagawa, A.,Fu, T.F.,Chen, C.J. Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition. Acta Crystallogr.,Sect.D, 71:1006-1021, 2015 Cited by PubMed: 25849409 DOI: 10.1107/S1399004715002928 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation