4QPD

Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with tetrahydrofolate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	10-formyltetrahydrofolate dehydrogenase	polymer	318	35456.4	2	UniProt (E3NZ06) Pfam (PF00551) Pfam (PF02911) In PDB	Danio rerio (leopard danio zebra danio zebra fish)
2	A, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
3	A, B	(6S)-5,6,7,8-TETRAHYDROFOLATE	non-polymer		445.4	3	Chemie (THG)
4		water	water		18.0	432	Chemie (HOH)

Sequence modifications

A, B: 1 - 311 (UniProt: E3NZ06)

PDB	External Database	Details
Glu 312	-	expression tag
His 313	-	expression tag
His 314	-	expression tag
His 315	-	expression tag
His 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70912.9
Non-Polymers*	Number of molecules	5
	Total formula weight	1548.5
All*	Total formula weight	72461.4

*Water molecules are not included.