4QPD
Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with tetrahydrofolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 10-formyltetrahydrofolate dehydrogenase | polymer | 318 | 35456.4 | 2 | UniProt (E3NZ06) Pfam (PF00551) Pfam (PF02911) | Danio rerio (leopard danio zebra danio zebra fish) | |
| 2 | C, E (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 3 | D, F, G (A, B) | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 3 | Chemie (THG) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 432 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 311 (UniProt: E3NZ06)
| PDB | External Database | Details |
|---|---|---|
| Glu 312 | - | expression tag |
| His 313 | - | expression tag |
| His 314 | - | expression tag |
| His 315 | - | expression tag |
| His 316 | - | expression tag |
| His 317 | - | expression tag |
| His 318 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70912.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1548.5 | |
| All* | Total formula weight | 72461.4 |
