4QNU

Crystal structure of CmoB bound with Cx-SAM in P21212

Summary for 4QNU

• Entry DOI: 10.2210/pdb4qnu/pdb
• Related: 4QNV 4QNX
• Descriptor: tRNA (mo5U34)-methyltransferase, (2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio] -2-ammoniobutanoate, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: structural genomics, psi-biology, new york structural genomics research consortium, nysgrc, rossmannfold, transferase
• Biological source: Escherichia coli
• Total number of polymer chains: 8
• Total formula weight: 300909.19

Authors

Kim, J.,Toro, R.,Bhosle, R.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC) (deposition date: 2014-06-18, release date: 2014-09-17, Last modification date: 2024-02-28)

• Primary citation: Kim, J.,Xiao, H.,Koh, J.,Wang, Y.,Bonanno, J.B.,Thomas, K.,Babbitt, P.C.,Brown, S.,Lee, Y.S.,Almo, S.C.; Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification.; Nucleic Acids Res., 43:4602-4613, 2015; PubMed: 25855808; DOI: 10.1093/nar/gkv206

Experimental method

X-RAY DIFFRACTION (2.6 Å)