4QN6

Crystal structure of Neuraminidase N6 complexed with Laninamivir

4QN6 の概要

• エントリーDOI: 10.2210/pdb4qn6/pdb
• 関連するPDBエントリー: 4QN3 4QN4 4QN5 4QN7
• 分子名称: Neuraminidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: 6-bladed beta-propeller, hydrolase, calcium binding, glycosylation
• 由来する生物種: Influenza A virus (A/chicken/Nanchang/7-010/2000(H3N6))
• 細胞内の位置: Virion membrane: Q2FCL6
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 90481.25

構造登録者

Sun, X.,Li, Q.,Wu, Y.,Liu, Y.,Qi, J.,Vavricka, C.J.,Gao, G.F. (登録日: 2014-06-17, 公開日: 2014-07-30, 最終更新日: 2023-11-08)

• 主引用文献: Sun, X.,Li, Q.,Wu, Y.,Wang, M.,Liu, Y.,Qi, J.,Vavricka, C.J.,Gao, G.F.; Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle.; J.Virol., 88:9197-9207, 2014; PubMed: 24899180; DOI: 10.1128/JVI.00805-14

実験手法

X-RAY DIFFRACTION (1.945 Å)