4QN7

Crystal structure of neuramnidase N7 complexed with Oseltamivir

Summary for 4QN7

• Entry DOI: 10.2210/pdb4qn7/pdb
• Related: 4QN3 4QN4 4QN5 4QN6
• Descriptor: Neuraminidase, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: 6-bladed beta-propeller, hydrolase, calcium binding, glycosylation
• Biological source: Influenza A virus (A/mallard/ALB/196/1996(H10N7))
• Cellular location: Virion membrane: Q20R18
• Total number of polymer chains: 2
• Total formula weight: 89023.30

Authors

Sun, X.,Li, Q.,Wu, Y.,Liu, Y.,Qi, J.,Vavricka, C.J.,Gao, G.F. (deposition date: 2014-06-17, release date: 2014-07-30, Last modification date: 2023-11-08)

• Primary citation: Sun, X.,Li, Q.,Wu, Y.,Wang, M.,Liu, Y.,Qi, J.,Vavricka, C.J.,Gao, G.F.; Structure of influenza virus N7: the last piece of the neuraminidase "jigsaw" puzzle.; J.Virol., 88:9197-9207, 2014; PubMed: 24899180; DOI: 10.1128/JVI.00805-14

Experimental method

X-RAY DIFFRACTION (2.302 Å)