4QN6
Crystal structure of Neuraminidase N6 complexed with Laninamivir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Neuraminidase | polymer | 391 | 43194.7 | 2 | UniProt (Q2FCL6) Pfam (PF00064) In PDB | Influenza A virus (A/chicken/Nanchang/7-010/2000(H3N6)) | |
| 2 | C, E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 3 | D, F | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1073.0 | 2 | In PDB GlyTouCan (G94106MV) | |||
| 4 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 5 | A, B | 5-acetamido-2,6-anhydro-4-carbamimidamido-3,4,5-trideoxy-7-O-methyl-D-glycero-D-galacto-non-2-enonic acid | non-polymer | 346.3 | 2 | Chemie (LNV) | |||
| 6 | water | water | 18.0 | 846 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 391 (UniProt: Q2FCL6)
| PDB | External Database | Details |
|---|---|---|
| Phe 2 | Lys 81 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86389.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 3319.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 772.8 | |
| All* | Total formula weight | 90481.3 |
