4QKX
Structure of beta2 adrenoceptor bound to a covalent agonist and an engineered nanobody
Summary for 4QKX
Entry DOI | 10.2210/pdb4qkx/pdb |
Descriptor | Beta-2 adrenergic receptor, R9 protein, SODIUM ION, ... (4 entities in total) |
Functional Keywords | 7-transmembrane helices, signal transduction, g proteins, membrane, membrane protein-immune system complex, membrane protein/immune system |
Biological source | Enterobacteria phage T4 More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P07550 |
Total number of polymer chains | 2 |
Total formula weight | 66810.86 |
Authors | Weichert, D.,Kruse, A.C.,Manglik, A.,Hiller, C.,Zhang, C.,Huebner, H.,Kobilka, B.K.,Gmeiner, P. (deposition date: 2014-06-10, release date: 2014-07-23, Last modification date: 2017-06-28) |
Primary citation | Weichert, D.,Kruse, A.C.,Manglik, A.,Hiller, C.,Zhang, C.,Hubner, H.,Kobilka, B.K.,Gmeiner, P. Covalent agonists for studying G protein-coupled receptor activation. Proc.Natl.Acad.Sci.USA, 111:10744-10748, 2014 Cited by PubMed: 25006259DOI: 10.1073/pnas.1410415111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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