4QGT

The Crystal Structure of Human IgG Fc Domain with Enhanced Aromatic Sequon

4QGT の概要

• エントリーDOI: 10.2210/pdb4qgt/pdb
• 関連するPDBエントリー: 2WAH 3AVE 4BM7
• 分子名称: Hepatitis B virus receptor binding protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: igg1, immunoglobulin-like beta-sandwich, immune system
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54972.86

構造登録者

Kong, L.,Connelly, S.C.,Wilson, I.A. (登録日: 2014-05-25, 公開日: 2015-04-08, 最終更新日: 2023-09-20)

• 主引用文献: Chen, W.,Kong, L.,Connelly, S.,Dendle, J.M.,Liu, Y.,Wilson, I.A.,Powers, E.T.,Kelly, J.W.; Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon.; Acs Chem.Biol., 11:1852-1861, 2016; PubMed: 27128252; DOI: 10.1021/acschembio.5b01035

実験手法

X-RAY DIFFRACTION (2.99 Å)