4QGC

crystal structure of PKM2-K422R mutant

Summary for 4QGC

• Entry DOI: 10.2210/pdb4qgc/pdb
• Related: 4QG6 4QG8 4QG9 4RPP
• Descriptor: Pyruvate kinase PKM, POTASSIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: tetramer, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P14618
• Total number of polymer chains: 4
• Total formula weight: 234762.02

Authors

Wang, P.,Sun, C.,Zhu, T.,Xu, Y. (deposition date: 2014-05-22, release date: 2015-02-25, Last modification date: 2022-08-24)

• Primary citation: Wang, P.,Sun, C.,Zhu, T.,Xu, Y.; Structural insight into mechanisms for dynamic regulation of PKM2.; Protein Cell, 6:275-287, 2015; PubMed: 25645022; DOI: 10.1007/s13238-015-0132-x

Experimental method

X-RAY DIFFRACTION (2.296 Å)