4QF8

Crystal Structure of the Complex of Phospholipase A2 with Spermidine at 1.65 A Resolution

Summary for 4QF8

• Entry DOI: 10.2210/pdb4qf8/pdb
• Related: 1FB2 4QEM 4QER 4QF7 4QGD
• Descriptor: Phospholipase A2 VRV-PL-VIIIa, SPERMIDINE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Daboia russellii pulchella
• Cellular location: Secreted : D0VX11
• Total number of polymer chains: 1
• Total formula weight: 13871.08

Authors

Shukla, P.K.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2014-05-20, release date: 2014-06-18, Last modification date: 2023-11-08)

• Primary citation: Shukla, P.K.,Gautam, L.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P.; Structures and binding studies of the complexes of phospholipase A2 with five inhibitors; Biochim.Biophys.Acta, 1854:269-277, 2015; PubMed: 25541253; DOI: 10.1016/j.bbapap.2014.12.017

Experimental method

X-RAY DIFFRACTION (1.65 Å)