4QBS

Crystal structure of DNMT3a ADD domain E545R mutant bound to H3T3ph peptide

Summary for 4QBS

Entry DOI	10.2210/pdb4qbs/pdb
Related	4QBQ 4QBR
Descriptor	DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION, ... (5 entities in total)
Functional Keywords	zinc finger, histone binding, transferase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus : Q9Y6K1
Total number of polymer chains	2
Total formula weight	16854.27
Authors	Wang, H.,Li, H. (deposition date: 2014-05-08, release date: 2015-05-13)
Primary citation	Noh, K.,Wang, H.,Kim, H.,Wenderski, W.,Fang, F.,Li, C.,Dewell, S.,Wu, X.,Ferris, A.,Hughes, S.H.,Zheng, D.,Melnick, A.M.,Patel, D.J.,Li, H.,Allis, C.D. Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs To be Published,
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation