4QBS
Crystal structure of DNMT3a ADD domain E545R mutant bound to H3T3ph peptide
Summary for 4QBS
Entry DOI | 10.2210/pdb4qbs/pdb |
Related | 4QBQ 4QBR |
Descriptor | DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION, ... (5 entities in total) |
Functional Keywords | zinc finger, histone binding, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9Y6K1 |
Total number of polymer chains | 2 |
Total formula weight | 16854.27 |
Authors | |
Primary citation | Noh, K.,Wang, H.,Kim, H.,Wenderski, W.,Fang, F.,Li, C.,Dewell, S.,Wu, X.,Ferris, A.,Hughes, S.H.,Zheng, D.,Melnick, A.M.,Patel, D.J.,Li, H.,Allis, C.D. Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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