4Q8Q

tRNA-Guanine Transglycosylase (TGT) Mutant V262C in Complex with 6-Amino-2-{[2-(morpholin-4-yl)ethyl]amino}-1H,7H,8H-imidazo[4,5-g]quinazolin-8-one

Summary for 4Q8Q

• Entry DOI: 10.2210/pdb4q8q/pdb
• Related: 1PUD 4Q8M 4Q8N 4Q8O 4Q8P
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, 6-amino-2-[(2-morpholin-4-ylethyl)amino]-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (4 entities in total)
• Functional Keywords: transferase, preq1, trna, guanine exchange enzyme, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Zymomonas mobilis subsp. mobilis
• Total number of polymer chains: 1
• Total formula weight: 43468.61

Authors

Neeb, M.,Heine, A.,Klebe, G. (deposition date: 2014-04-28, release date: 2015-05-20, Last modification date: 2023-09-20)

• Primary citation: Neeb, M.,Heine, A.,Klebe, G.; Creating a Resistance Model for TGT: The Effect of Mutations on Flexible lin-Benzoguanine Substituents; To be Published,

Experimental method

X-RAY DIFFRACTION (1.721 Å)