4Q81
Crystal structure of 1-hydroxy-4,6-dimethylpyridine-2(1H)-thione bound to human carbonic anhydrase II
Summary for 4Q81
Entry DOI | 10.2210/pdb4q81/pdb |
Related | 3M1K 4Q7P 4Q7S 4Q7V 4Q7W 4Q83 4Q87 4Q8X 4Q8Y 4Q8Z 4Q90 4Q99 4Q9Y |
Descriptor | Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (6 entities in total) |
Functional Keywords | lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29909.52 |
Authors | Martin, D.P.,Cohen, S.M. (deposition date: 2014-04-25, release date: 2015-03-11, Last modification date: 2023-09-20) |
Primary citation | Martin, D.P.,Blachly, P.G.,McCammon, J.A.,Cohen, S.M. Exploring the influence of the protein environment on metal-binding pharmacophores. J.Med.Chem., 57:7126-7135, 2014 Cited by PubMed: 25116076DOI: 10.1021/jm500984b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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