4Q3R

Crystal structure of Schistosoma mansoni arginase in complex with inhibitor ABHDP

Summary for 4Q3R

• Entry DOI: 10.2210/pdb4q3r/pdb
• Related: 4Q3P 4Q3Q 4Q3S 4Q3T 4Q3U 4Q3V 4Q40 4Q41 4Q42
• Descriptor: Arginase, MANGANESE (II) ION, CESIUM ION, ... (9 entities in total)
• Functional Keywords: arginase-deacetylase fold, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Schistosoma mansoni (Blood fluke); More
• Total number of polymer chains: 4
• Total formula weight: 173583.75

Authors

Hai, Y.,Edwards, J.E.,Van Zandt, M.C.,Hoffmann, K.F.,Christianson, D.W. (deposition date: 2014-04-12, release date: 2014-07-16, Last modification date: 2023-12-06)

• Primary citation: Hai, Y.,Edwards, J.E.,Van Zandt, M.C.,Hoffmann, K.F.,Christianson, D.W.; Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.; Biochemistry, 53:4671-4684, 2014; PubMed: 25007099; DOI: 10.1021/bi5004519

Experimental method

X-RAY DIFFRACTION (2.169 Å)