4Q3R
Crystal structure of Schistosoma mansoni arginase in complex with inhibitor ABHDP
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Arginase | polymer | 385 | 42283.3 | 2 | UniProt (Q6WVP6) Pfam (PF00491) In PDB | Schistosoma mansoni (Blood fluke) | |
2 | C, D | Arginase | polymer | 385 | 42267.3 | 2 | UniProt (Q6WVP6) Pfam (PF00491) In PDB | Schistosoma mansoni (Blood fluke) | |
3 | C, A, D, B | MANGANESE (II) ION | non-polymer | 54.9 | 8 | Chemie (MN) | |||
4 | C, A, D, B | CESIUM ION | non-polymer | 132.9 | 11 | Chemie (CS) | |||
5 | C, A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
6 | C, A, D, B | (R)-2-amino-6-borono-2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)hexanoic acid | non-polymer | 434.1 | 4 | Chemie (XA2) | |||
7 | C, A, B | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
8 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
9 | water | water | 18.0 | 627 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 364 (UniProt: Q6WVP6)
C, D: 1 - 364 (UniProt: Q6WVP6)
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Leu -7 | - | expression tag |
Val -6 | - | expression tag |
Pro -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Met -20 | - | expression tag |
Gly -19 | - | expression tag |
Ser -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Leu -7 | - | expression tag |
Val -6 | - | expression tag |
Pro -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 169101.2 | |
Non-Polymers* | Number of molecules | 34 |
Total formula weight | 4482.6 | |
All* | Total formula weight | 173583.7 |