4Q3T

Crystal structure of Schistosoma mansoni arginase in complex with inhibitor NOHA

Summary for 4Q3T

Entry DOI	10.2210/pdb4q3t/pdb
Related	4Q3P 4Q3Q 4Q3R 4Q3S 4Q3U 4Q3V 4Q40 4Q41 4Q42
Descriptor	Arginase, MANGANESE (II) ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	arginase-deacetylase fold, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Schistosoma mansoni (Blood fluke)
Total number of polymer chains	4
Total formula weight	170822.04
Authors	Hai, Y.,Edwards, J.E.,Van Zandt, M.C.,Hoffmann, K.F.,Christianson, D.W. (deposition date: 2014-04-12, release date: 2014-07-16, Last modification date: 2023-09-20)
Primary citation	Hai, Y.,Edwards, J.E.,Van Zandt, M.C.,Hoffmann, K.F.,Christianson, D.W. Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53:4671-4684, 2014 Cited by PubMed: 25007099 DOI: 10.1021/bi5004519 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.142 Å)

Structure validation