4Q0O

Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand

4Q0O の概要

• エントリーDOI: 10.2210/pdb4q0o/pdb
• 関連するPDBエントリー: 4Q0N
• 分子名称: Protein polybromo-1, POTASSIUM ION, (2E)-1-(2-hydroxyphenyl)-3-[(3R)-3-phenylpiperidin-1-yl]prop-2-en-1-one, ... (4 entities in total)
• 機能のキーワード: pb1, polybromo 1 isoform 1, baf180, polybromo-1d, pbrm1, brg1-associated factor 180, bromodomain, chromatin regulator, dna-binding, nucleus, transcription, transcription regulation, structural genomics consortium, sgc
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: Q86U86
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14994.48

構造登録者

Filippakopoulos, P.,Picaud, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2014-04-02, 公開日: 2014-05-07, 最終更新日: 2023-09-20)

• 主引用文献: Filippakopoulos, P.,Picaud, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC); Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand; To be Published,

実験手法

X-RAY DIFFRACTION (1.83 Å)