4Q0O
Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein polybromo-1 | polymer | 124 | 14648.0 | 1 | UniProt (Q86U86) Pfam (PF00439) | Homo sapiens (human) | hPB1, BRG1-associated factor 180, BAF180, Polybromo-1D |
| 2 | B (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 3 | C (A) | (2E)-1-(2-hydroxyphenyl)-3-[(3R)-3-phenylpiperidin-1-yl]prop-2-en-1-one | non-polymer | 307.4 | 1 | Chemie (2XC) | |||
| 4 | D (A) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 613 - 734 (UniProt: Q86U86)
| PDB | External Database | Details |
|---|---|---|
| Ser 611 | - | expression tag |
| Met 612 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14648.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 346.5 | |
| All* | Total formula weight | 14994.5 |
