4PYM
humanized rat apo-COMT bound to sulphate
Summary for 4PYM
Entry DOI | 10.2210/pdb4pym/pdb |
Related | 4P7F 4P7G 4P7J 4P7K 4PYI 4PYJ 4PYK 4PYL 4PYN 4PYO 4PYQ |
Descriptor | Catechol O-methyltransferase, POTASSIUM ION, SULFATE ION, ... (4 entities in total) |
Functional Keywords | methyltransferase, neurotransmitter degradation, alternative initiation, catecholamine metabolism, cell membrane, metal-binding, phosphoprotein, signal-anchor, transmembrane anchor, enzyme mechanism, conformational change, transferase |
Biological source | Rattus norvegicus (brown rat,rat,rats) |
Cellular location | Isoform 2: Cytoplasm. Isoform 1: Cell membrane; Single-pass type II membrane protein; Extracellular side: P22734 |
Total number of polymer chains | 1 |
Total formula weight | 24829.49 |
Authors | Ehler, A.,Benz, J.,Schlatter, D.,Rudolph, M.G. (deposition date: 2014-03-27, release date: 2014-06-11, Last modification date: 2024-02-28) |
Primary citation | Ehler, A.,Benz, J.,Schlatter, D.,Rudolph, M.G. Mapping the conformational space accessible to catechol-O-methyltransferase. Acta Crystallogr.,Sect.D, 70:2163-2174, 2014 Cited by PubMed: 25084335DOI: 10.1107/S1399004714012917 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.19 Å) |
Structure validation
Download full validation report