4P7F

Mouse apo-COMT

Summary for 4P7F

• Entry DOI: 10.2210/pdb4p7f/pdb
• Related: 4P7G 4P7J 4P7K
• Descriptor: Catechol O-methyltransferase, SODIUM ION, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: methyltransferase, neurotransmitter degradation, transferase, alternative initiation, catecholamine metabolism, cell membrane, metal-binding, phosphoprotein, s-adenosyl-l-methionine, signal-anchor, transmembrane anchor, enzyme mechanism, conformational change
• Biological source: Mus musculus (Mouse)
• Cellular location: Isoform Soluble: Cytoplasm. Isoform Membrane-bound: Cell membrane; Single-pass type II membrane protein; Extracellular side: O88587
• Total number of polymer chains: 1
• Total formula weight: 25339.29

Authors

Ehler, A.,Benz, J.,Schlatter, D.,Rudolph, M.G. (deposition date: 2014-03-27, release date: 2014-06-11, Last modification date: 2023-12-27)

• Primary citation: Ehler, A.,Benz, J.,Schlatter, D.,Rudolph, M.G.; Mapping the conformational space accessible to catechol-O-methyltransferase.; Acta Crystallogr.,Sect.D, 70:2163-2174, 2014; PubMed: 25084335; DOI: 10.1107/S1399004714012917

Experimental method

X-RAY DIFFRACTION (1.37 Å)