4PY8

Crystal structure of Fab 3.1 in complex with the 1918 influenza virus hemagglutinin

Summary for 4PY8

• Entry DOI: 10.2210/pdb4py8/pdb
• Related: 4PY7
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, antibody 3.1 heavy chain, ... (7 entities in total)
• Functional Keywords: hemagglutinin glycoproteins, immunoglobulin fab fragment, membrane fusion, neutralizing antibodies, viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus; More
• Cellular location: Virion membrane; Single-pass type I membrane protein (Potential): Q9WFX3 Q9WFX3
• Total number of polymer chains: 4
• Total formula weight: 104681.52

Authors

Dreyfus, C. (deposition date: 2014-03-26, release date: 2014-05-21, Last modification date: 2020-07-29)

• Primary citation: Wyrzucki, A.,Dreyfus, C.,Kohler, I.,Steck, M.,Wilson, I.A.,Hangartner, L.; Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a VH3-30-Encoded Heterosubtypic Antibody.; J.Virol., 88:7083-7092, 2014; PubMed: 24719426; DOI: 10.1128/JVI.00178-14

Experimental method

X-RAY DIFFRACTION (2.91 Å)