4PY8

Crystal structure of Fab 3.1 in complex with the 1918 influenza virus hemagglutinin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hemagglutinin HA1 chain	polymer	331	36452.8	1	UniProt (Q9WFX3) Pfam (PF00509)	Influenza A virus
2	B (B)	Hemagglutinin HA2 chain	polymer	179	20394.4	1	UniProt (Q9WFX3) Pfam (PF00509)	Influenza A virus
3	C (I)	antibody 3.1 heavy chain	polymer	219	23603.7	1		Homo sapiens (human)
4	D (J)	antibody 3.1 light chain	polymer	214	23159.7	1		Homo sapiens (human)
5	E (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	F, G (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
7	H, I (I, J)	MALONATE ION	non-polymer		102.0	2	Chemie (MLI)

Sequence modifications

A: 11 - 337 (UniProt: Q9WFX3)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag

B: 1 - 176 (UniProt: Q9WFX3)

PDB	External Database	Details
Ser 177	-	expression tag
Gly 178	-	expression tag
Arg 179	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	103610.6
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	4
	Total formula weight	646.5
All*	Total formula weight	104681.5

*Water molecules are not included.