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4PXU

Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers

Summary for 4PXU
Entry DOI10.2210/pdb4pxu/pdb
Related4PXT
DescriptorBipolar kinesin KRP-130, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywordscoiled-coil, bipolar assembly domain of kinesin-5, bipolar tetramers, anti-parallel four-helix bundle, kinesin-5 functions via a "sliding filament" mechanism, crosslinking adjacent microtubules into bundles throughout the mitotic spindle, microtubules, cell cycle
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains2
Total formula weight48584.97
Authors
Scholey, J.E.,Nithianantham, S.,Scholey, J.M.,Al-Bassam, J. (deposition date: 2014-03-25, release date: 2014-04-23, Last modification date: 2023-09-20)
Primary citationScholey, J.E.,Nithianantham, S.,Scholey, J.M.,Al-Bassam, J.
Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers.
Elife, 3:e02217-e02217, 2014
Cited by
PubMed: 24714498
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.601 Å)
Structure validation

217705

數據於2024-03-27公開中

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