4PXU

Structural basis for the assembly of the mitotic motor kinesin-5 into bipolar tetramers

4PXU の概要

• エントリーDOI: 10.2210/pdb4pxu/pdb
• 関連するPDBエントリー: 4PXT
• 分子名称: Bipolar kinesin KRP-130, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
• 機能のキーワード: coiled-coil, bipolar assembly domain of kinesin-5, bipolar tetramers, anti-parallel four-helix bundle, kinesin-5 functions via a "sliding filament" mechanism, crosslinking adjacent microtubules into bundles throughout the mitotic spindle, microtubules, cell cycle
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48584.97

構造登録者

Scholey, J.E.,Nithianantham, S.,Scholey, J.M.,Al-Bassam, J. (登録日: 2014-03-25, 公開日: 2014-04-23, 最終更新日: 2023-09-20)

• 主引用文献: Scholey, J.E.,Nithianantham, S.,Scholey, J.M.,Al-Bassam, J.; Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers.; Elife, 3:e02217-e02217, 2014; PubMed: 24714498

実験手法

X-RAY DIFFRACTION (2.601 Å)