4PWN
Crystal structure of Active WNK1 kinase
Summary for 4PWN
| Entry DOI | 10.2210/pdb4pwn/pdb |
| Related | 3FPQ 4Q2A |
| Descriptor | Serine/threonine-protein kinase WNK1, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | kinase, wnk1, ser/thr protein kinase, serine/threonine kinase, atp-binding, phosphorylation, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm : Q9H4A3 |
| Total number of polymer chains | 1 |
| Total formula weight | 31633.52 |
| Authors | Piala, A.,Moon, T.,Akella, T.,He, H.,Cobbm, M.H.,Goldsmith, E. (deposition date: 2014-03-20, release date: 2014-05-28, Last modification date: 2023-09-20) |
| Primary citation | Piala, A.T.,Moon, T.M.,Akella, R.,He, H.,Cobb, M.H.,Goldsmith, E.J. Chloride Sensing by WNK1 Involves Inhibition of Autophosphorylation. Sci.Signal., 7:ra41-ra41, 2014 Cited by PubMed: 24803536DOI: 10.1126/scisignal.2005050 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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