4PUF

Complex between the Salmonella T3SS effector SlrP and its human target thioredoxin-1

4PUF の概要

• エントリーDOI: 10.2210/pdb4puf/pdb
• 分子名称: E3 ubiquitin-protein ligase SlrP, Thioredoxin (2 entities in total)
• 機能のキーワード: lrr domain, nel domain, e3 ubiquitin ligase, human thioredoxin 1, ligase -oxidoreductase complex, ligase-oxidoreductase complex, ligase/oxidoreductase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium; 詳細
• 細胞内の位置: Secreted: D0ZRB2; Nucleus: P10599
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 172247.14

構造登録者

Zouhir, S.,Bernal-Bayard, J.,Cordero-Alba, M.,Cardenal-Munoz, E.,Guimaraes, B.,Lazar, N.,Ramos-Morales, F.,Nessler, S. (登録日: 2014-03-13, 公開日: 2014-09-17, 最終更新日: 2024-02-28)

• 主引用文献: Zouhir, S.,Bernal-Bayard, J.,Cordero-Alba, M.,Cardenal-Munoz, E.,Guimaraes, B.,Lazar, N.,Ramos-Morales, F.,Nessler, S.; The structure of the Slrp-Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family.; Biochem.J., 464:135-144, 2014; PubMed: 25184225; DOI: 10.1042/BJ20140587

実験手法

X-RAY DIFFRACTION (3.296 Å)