4PQT
Insights into the mechanism of deubiquitination by JAMM deubiquitinases from co-crystal structures of enzyme with substrate and product
Summary for 4PQT
Entry DOI | 10.2210/pdb4pqt/pdb |
Related | 2ZNV 4K1R |
Descriptor | AMSH-like protease sst2, Protein UBBP4, ZINC ION, ... (5 entities in total) |
Functional Keywords | helix-beta-helix sandwich, ubiquitin, deubiquitination, zinc metalloprotease, lysine 63-linked polyubiquitin, hydrolase-transcription complex, hydrolase/transcription |
Biological source | Schizosaccharomyces pombe (Fission yeast) More |
Cellular location | Cytoplasm: Q9P371 |
Total number of polymer chains | 2 |
Total formula weight | 31177.62 |
Authors | Shrestha, R.K.,Ronau, J.A.,Das, C. (deposition date: 2014-03-04, release date: 2014-06-18, Last modification date: 2023-09-20) |
Primary citation | Shrestha, R.K.,Ronau, J.A.,Davies, C.W.,Guenette, R.G.,Strieter, E.R.,Paul, L.N.,Das, C. Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product. Biochemistry, 53:3199-3217, 2014 Cited by PubMed: 24787148DOI: 10.1021/bi5003162 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report