4PQT

Insights into the mechanism of deubiquitination by JAMM deubiquitinases from co-crystal structures of enzyme with substrate and product

4PQT の概要

• エントリーDOI: 10.2210/pdb4pqt/pdb
• 関連するPDBエントリー: 2ZNV 4K1R
• 分子名称: AMSH-like protease sst2, Protein UBBP4, ZINC ION, ... (5 entities in total)
• 機能のキーワード: helix-beta-helix sandwich, ubiquitin, deubiquitination, zinc metalloprotease, lysine 63-linked polyubiquitin, hydrolase-transcription complex, hydrolase/transcription
• 由来する生物種: Schizosaccharomyces pombe (Fission yeast); 詳細
• 細胞内の位置: Cytoplasm: Q9P371
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 31177.62

構造登録者

Shrestha, R.K.,Ronau, J.A.,Das, C. (登録日: 2014-03-04, 公開日: 2014-06-18, 最終更新日: 2023-09-20)

• 主引用文献: Shrestha, R.K.,Ronau, J.A.,Davies, C.W.,Guenette, R.G.,Strieter, E.R.,Paul, L.N.,Das, C.; Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.; Biochemistry, 53:3199-3217, 2014; PubMed: 24787148; DOI: 10.1021/bi5003162

実験手法

X-RAY DIFFRACTION (2.05 Å)