4PP4

Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication

Summary for 4PP4

Entry DOI	10.2210/pdb4pp4/pdb
Related	3WRN 3WRO 3WRQ 3WRR 3WRS
Descriptor	Non-capsid protein NS-1, BETA-MERCAPTOETHANOL, SODIUM ION, ... (4 entities in total)
Functional Keywords	nuclease activity, single/double strand dna binding, nicking protein, replication
Biological source	Murine minute virus (MVM)
Total number of polymer chains	1
Total formula weight	32490.51
Authors	Tewary, S.K.,Zhao, H.,Tang, L. (deposition date: 2014-02-26, release date: 2015-01-21, Last modification date: 2024-03-20)
Primary citation	Tewary, S.K.,Liang, L.,Lin, Z.,Lynn, A.,Cotmore, S.F.,Tattersall, P.,Zhao, H.,Tang, L. Structures of minute virus of mice replication initiator protein N-terminal domain: Insights into DNA nicking and origin binding. Virology, 476C:61-71, 2014 Cited by PubMed: 25528417 DOI: 10.1016/j.virol.2014.11.022 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation