4PP4
Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique Zn2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BME A 301 |
| Chain | Residue |
| A | VAL25 |
| A | PHE26 |
| A | PHE137 |
| A | SER138 |
| A | GLN139 |
| A | CYS200 |
| A | HOH458 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 302 |
| Chain | Residue |
| A | SER230 |
| A | SER231 |
| A | HOH409 |
| A | ASP91 |
| A | VAL116 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 303 |
| Chain | Residue |
| A | LYS49 |
| A | GLU50 |
| A | LEU51 |
| A | HOH401 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 304 |
| Chain | Residue |
| A | THR83 |
| A | SER220 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"Ori-binding","evidences":[{"source":"PubMed","id":"25528417","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Motif: {"description":"RCR-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01366","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Motif: {"description":"RCR-3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01366","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For nuclease activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01366","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25528417","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01366","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25528417","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
