4PMW
Structure of mouse Dis3L2 in complex with oligoU RNA substrate
Summary for 4PMW
Entry DOI | 10.2210/pdb4pmw/pdb |
Descriptor | DIS3-like exonuclease 2, U-U-U-U-U-U-U-U-U-U-U-U-U-U, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | mirna regulation, exonuclease, rna complex, rna interference, hydrolase-rna complex, hydrolase/rna |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 182772.87 |
Authors | Faehnle, C.R.,Walleshauser, J.,Joshua-Tor, L. (deposition date: 2014-05-22, release date: 2014-07-30, Last modification date: 2023-12-27) |
Primary citation | Faehnle, C.R.,Walleshauser, J.,Joshua-Tor, L. Mechanism of Dis3l2 substrate recognition in the Lin28-let-7 pathway. Nature, 514:252-256, 2014 Cited by PubMed: 25119025DOI: 10.1038/nature13553 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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