4PMW

Structure of mouse Dis3L2 in complex with oligoU RNA substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	DIS3-like exonuclease 2	polymer	770	87120.8	2	UniProt (Q8CI75) Pfam (PF17216) Pfam (PF17849) Pfam (PF00773) Pfam (PF17877) In PDB	Mus musculus (Mouse)
2	C, D	U-U-U-U-U-U-U-U-U-U-U-U-U-U	polymer	14	4241.4	2		unidentified
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4		water	water		18.0	6	Chemie (HOH)

Sequence modifications

A, B: 37 - 856 (UniProt: Q8CI75)

PDB	External Database	Details
-	His 148	deletion
-	His 149	deletion
-	Pro 150	deletion
-	Leu 151	deletion
-	Gln 152	deletion
-	Gln 153	deletion
-	Ser 154	deletion
-	Arg 155	deletion
-	Lys 156	deletion
-	Gly 157	deletion
-	Trp 158	deletion
-	Ser 159	deletion
-	Gly 160	deletion
-	Pro 161	deletion
-	Asp 162	deletion
-	Val 163	deletion
-	Ile 164	deletion
-	Ile 165	deletion
-	Glu 166	deletion
-	Ala 167	deletion
-	Gln 168	deletion
-	Phe 169	deletion
-	Ser 194	deletion
-	Thr 195	deletion
-	Pro 196	deletion
-	Asp 197	deletion
-	Arg 198	deletion
-	Gly 199	deletion
-	Lys 200	deletion
-	Glu 201	deletion
-	Asp 202	deletion
-	Ser 203	deletion
-	Ser 204	deletion
-	Thr 205	deletion
-	Pro 206	deletion
-	Val 207	deletion
-	Met 208	deletion
-	Lys 209	deletion
-	Asp 210	deletion
-	Glu 211	deletion
-	Asn 212	deletion
-	Thr 213	deletion
-	Pro 214	deletion
-	Ile 215	deletion
-	Pro 216	deletion
-	Gln 217	deletion
-	Asp 218	deletion
-	Thr 219	deletion
-	Arg 220	deletion
-	Gly 221	deletion
Asn 389	Asp 389	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	182724.3
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	182772.9

*Water molecules are not included.