4PMW
Structure of mouse Dis3L2 in complex with oligoU RNA substrate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DIS3-like exonuclease 2 | polymer | 770 | 87120.8 | 2 | UniProt (Q8CI75) Pfam (PF17216) Pfam (PF17849) Pfam (PF00773) Pfam (PF17877) | Mus musculus (Mouse) | |
| 2 | C, D (C, D) | U-U-U-U-U-U-U-U-U-U-U-U-U-U | polymer | 14 | 4241.4 | 2 | unidentified | ||
| 3 | E, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B: 37 - 856 (UniProt: Q8CI75)
| PDB | External Database | Details |
|---|---|---|
| - | His 148 | deletion |
| - | His 149 | deletion |
| - | Pro 150 | deletion |
| - | Leu 151 | deletion |
| - | Gln 152 | deletion |
| - | Gln 153 | deletion |
| - | Ser 154 | deletion |
| - | Arg 155 | deletion |
| - | Lys 156 | deletion |
| - | Gly 157 | deletion |
| - | Trp 158 | deletion |
| - | Ser 159 | deletion |
| - | Gly 160 | deletion |
| - | Pro 161 | deletion |
| - | Asp 162 | deletion |
| - | Val 163 | deletion |
| - | Ile 164 | deletion |
| - | Ile 165 | deletion |
| - | Glu 166 | deletion |
| - | Ala 167 | deletion |
| - | Gln 168 | deletion |
| - | Phe 169 | deletion |
| - | Ser 194 | deletion |
| - | Thr 195 | deletion |
| - | Pro 196 | deletion |
| - | Asp 197 | deletion |
| - | Arg 198 | deletion |
| - | Gly 199 | deletion |
| - | Lys 200 | deletion |
| - | Glu 201 | deletion |
| - | Asp 202 | deletion |
| - | Ser 203 | deletion |
| - | Ser 204 | deletion |
| - | Thr 205 | deletion |
| - | Pro 206 | deletion |
| - | Val 207 | deletion |
| - | Met 208 | deletion |
| - | Lys 209 | deletion |
| - | Asp 210 | deletion |
| - | Glu 211 | deletion |
| - | Asn 212 | deletion |
| - | Thr 213 | deletion |
| - | Pro 214 | deletion |
| - | Ile 215 | deletion |
| - | Pro 216 | deletion |
| - | Gln 217 | deletion |
| - | Asp 218 | deletion |
| - | Thr 219 | deletion |
| - | Arg 220 | deletion |
| - | Gly 221 | deletion |
| Asn 389 | Asp 389 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 182724.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 182772.9 |
