4PC8
Structure-based protein engineering efforts on the scaffold of a monomeric triosephosphate isomerase yielding a sugar isomerase
Summary for 4PC8
Entry DOI | 10.2210/pdb4pc8/pdb |
Related | 1AG1 1DKW 1IIG 1ML1 1MSS 1MTM 1TPD 1TPE 1TRI 2VEK 2VEL 5TIM |
Descriptor | Ma21-TIM, GLYCOLIC ACID (3 entities in total) |
Functional Keywords | triosephosphate isomerase tim barrel protein engineering substrate specificity, isomerase |
Biological source | Trypanosoma brucei brucei |
Total number of polymer chains | 1 |
Total formula weight | 25851.56 |
Authors | Krause, M.,Neubauer, P.,Wierenga, R.K. (deposition date: 2014-04-14, release date: 2015-04-22, Last modification date: 2023-11-15) |
Primary citation | Krause, M.,Kiema, T.R.,Neubauer, P.,Wierenga, R.K. Crystal structures of two monomeric triosephosphate isomerase variants identified via a directed-evolution protocol selecting for L-arabinose isomerase activity. Acta Crystallogr.,Sect.F, 72:490-499, 2016 Cited by PubMed: 27303904DOI: 10.1107/S2053230X16007548 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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