4PAM
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Summary for 4PAM
Entry DOI | 10.2210/pdb4pam/pdb |
Related | 4PAN 4PAO 4PAQ |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ... (5 entities in total) |
Functional Keywords | activation of heterotrimeric g protein, gdp release, computer modeling, g protein coupled receptors, rhodopsin, signaling protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 1 |
Total formula weight | 40913.72 |
Authors | Kaya, A.I.,Lokits, A.D.,Gilbert, J.,Iverson, T.M.,Meiler, J.,Hamm, H.E. (deposition date: 2014-04-09, release date: 2014-07-30, Last modification date: 2023-09-27) |
Primary citation | Kaya, A.I.,Lokits, A.D.,Gilbert, J.A.,Iverson, T.M.,Meiler, J.,Hamm, H.E. A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit. J.Biol.Chem., 289:24475-24487, 2014 Cited by PubMed: 25037222DOI: 10.1074/jbc.M114.572875 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.101 Å) |
Structure validation
Download full validation report