4PAM
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40355.0 | 1 | UniProt (P10824) Pfam (PF00503) | Rattus norvegicus (Rat) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | C (A) | SULFITE ION | non-polymer | 80.1 | 1 | Chemie (SO3) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 1 - 354 (UniProt: P10824)
| PDB | External Database | Details |
|---|---|---|
| Cys 336 | Phe 336 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40355.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 558.7 | |
| All* | Total formula weight | 40913.7 |
