4PAM
A conserved phenylalanine as relay between the 5 helix and the GDP binding region of heterotrimeric G protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 354 | 40355.0 | 1 | UniProt (P10824) Pfam (PF00503) | Rattus norvegicus (Rat) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) PubChem (136073927) | |||
| 3 | C (A) | SULFITE ION | non-polymer | 80.1 | 1 | Chemie (SO3) PubChem (1099) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 5 | E (A) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A: 1 - 354 (UniProt: P10824)
| PDB | External Database | Details |
|---|---|---|
| Cys 336 | Phe 336 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40355.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 558.7 | |
| All* | Total formula weight | 40913.7 |
