4P42
Extended-Synaptotagmin 2, SMP - C2A - C2B Domains
Summary for 4P42
Entry DOI | 10.2210/pdb4p42/pdb |
Descriptor | Extended synaptotagmin-2, 2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX Y}-ETHOXY)-ETHANOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... (4 entities in total) |
Functional Keywords | endocytosis, signal transduction, membrane contact site, lipid binding, lipid transport |
Biological source | Homo sapiens (Human) |
Cellular location | Cell membrane; Peripheral membrane protein: A0FGR8 |
Total number of polymer chains | 2 |
Total formula weight | 111114.22 |
Authors | Schauder, C.M.,Wu, X.,Reinisch, K.M. (deposition date: 2014-03-10, release date: 2014-05-14, Last modification date: 2023-12-27) |
Primary citation | Schauder, C.M.,Wu, X.,Saheki, Y.,Narayanaswamy, P.,Torta, F.,Wenk, M.R.,De Camilli, P.,Reinisch, K.M. Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer. Nature, 510:552-555, 2014 Cited by PubMed: 24847877DOI: 10.1038/nature13269 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.44 Å) |
Structure validation
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