4OWO
Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 6-fluoroanthranilate, PRPP and Magnesium
Summary for 4OWO
| Entry DOI | 10.2210/pdb4owo/pdb |
| Related | 4OWM 4OWN 4OWQ 4OWS 4OWU 4OWV |
| Descriptor | Anthranilate phosphoribosyltransferase, MAGNESIUM ION, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ... (7 entities in total) |
| Functional Keywords | anthranilic acids, magnesium, tryptophan, inhibitor, transferase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 2 |
| Total formula weight | 79541.00 |
| Authors | Castell, A.,Cookson, T.V.M.,Short, F.L.,Lott, J.S. (deposition date: 2014-02-02, release date: 2014-04-23, Last modification date: 2023-12-27) |
| Primary citation | Cookson, T.V.,Castell, A.,Bulloch, E.M.,Evans, G.L.,Short, F.L.,Baker, E.N.,Lott, J.S.,Parker, E.J. Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis. Biochem.J., 461:87-98, 2014 Cited by PubMed: 24712732DOI: 10.1042/BJ20140209 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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