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4OWO

Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with 6-fluoroanthranilate, PRPP and Magnesium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Anthranilate phosphoribosyltransferasepolymer37838848.92UniProt (P66992)
Pfam (PF02885)
Pfam (PF00591)
UniProt (by SIFTS) (P9WFX5)
Mycobacterium tuberculosis
2C, D, J, K
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3E, L
(A, B)
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranosenon-polymer390.12Chemie (PRP)
4F, G, M, N
(A, B)
2-azanyl-6-fluoranyl-benzoic acidnon-polymer155.14Chemie (6F0)
5H, I, O
(A, B)
GLYCEROLnon-polymer92.13Chemie (GOL)
6P
(B)
IMIDAZOLEnon-polymer69.11Chemie (IMD)
7Q, R
(A, B)
waterwater18.0513Chemie (HOH)
Sequence modifications
A, B: 1 - 370 (UniProt: P66992)
PDBExternal DatabaseDetails
Leu 371-expression tag
Glu 372-expression tag
His 373-expression tag
His 374-expression tag
His 375-expression tag
His 376-expression tag
His 377-expression tag
His 378-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight77697.8
Non-Polymers*Number of molecules14
Total formula weight1843.2
All*Total formula weight79541.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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