4OW8
Crystal structure of kinase domain of PknA from Mtb
Summary for 4OW8
| Entry DOI | 10.2210/pdb4ow8/pdb |
| Descriptor | Serine/threonine-protein kinase PknA, GLYCEROL, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | pkna, kinase, drug target, mtb, transferase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 30637.18 |
| Authors | Ravala, S.K.,Singh, S.,Yadav, G.S.,Karthikeyan, S.,Chakraborti, P.K. (deposition date: 2014-01-31, release date: 2015-02-04, Last modification date: 2023-09-27) |
| Primary citation | Ravala, S.K.,Singh, S.,Yadav, G.S.,Kumar, S.,Karthikeyan, S.,Chakraborti, P.K. Evidence that phosphorylation of threonine in the GT motif triggers activation of PknA, a eukaryotic-type serine/threonine kinase from Mycobacterium tuberculosis. Febs J., 282:1419-1431, 2015 Cited by PubMed: 25665034DOI: 10.1111/febs.13230 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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