4OQI

Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutations

Summary for 4OQI

Entry DOI	10.2210/pdb4oqi/pdb
Related	4IBR 4IBX 4OP5 4OP8 4OPQ 4OPR 4OPY 4OPZ 4OQ0 4OQG 4OQH
Descriptor	TEM-94 ES-beta-lactamase, CALCIUM ION, SULFATE ION, ... (4 entities in total)
Functional Keywords	beta-lctamase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	28866.83
Authors	Dellus-Gur, E.,Elias, M.,Fraser, J.S.,Tawfik, D.S. (deposition date: 2014-02-09, release date: 2015-05-20, Last modification date: 2018-01-17)
Primary citation	Dellus-Gur, E.,Elias, M.,Caselli, E.,Prati, F.,Salverda, M.L.,de Visser, J.A.,Fraser, J.S.,Tawfik, D.S. Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427:2396-2409, 2015 Cited by PubMed: 26004540 DOI: 10.1016/j.jmb.2015.05.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.13 Å)

Structure validation